3-years observational, patient management, global study on shortening door-to-needle time.


Status: Initiated
Type of study: 3-years observational, patient management, global study on shortening door-to-needle time.
Location: Global


SITS-WATCH project aims to reduce the delay between arriving at hospital and initiation of thrombolysis (door-to-needle time, DNT) from 65 minutes, which is the median value in SITS, to median below 40 minutes, i.e., for at least half of all patients. For some centers: 10-15% reduction.

Initial phase of the project

Participating centers will be asked about the hospital’s ability to shorten the processing time, whereby a specific program of change will be identified. With this program as a basis, participating centers define a plan for change to achieve the goal a median DNT below 40 minutes.

Pre-defined Survey Form will be distributed to SITS centres. The form includes variables about:

  • Education (FAST)
  • Transport (EMS)
  • Hospital procedures
  • Free comments

Follow-up phase

A list of potential interventions to reduce DNT will be delivered to each center, and the items that can be applied in each specific center will be discussed

  • Centers will be asked whether their planned improvements could be implemented
  • SITS will provide regular reports on the development of door to needle time during the project
  • DNT realized/materialized improvements will be monitored quarterly for the period of 1 year.


Results will be continuously presented anonymously for all participating centers and implementation of planned changes reported. 
Comparison at the country level will be reported regularly. The aim is to stimulate a global change in the treatment of acute stroke

Final reporting

  • The project is expected to last until the end of 2014
  • The project does not intend to reveal individual centre results
  • A publication of the most successful participants will be considered and implemented in consultation with all participants

 "SITS-WATCH - 3-year observational, global, patient management study on shortening door-to-needle time in IV thrombolysis. The study has been completed and the main results of are currently in preparation for publication."